IVF

Introduction

In vitro fertilisation (IVF) is one of several techniques available to helppeople with fertility problems have a baby.

During IVF, an egg is removed from the woman's ovaries and fertilised with sperm in a laboratory. The fertilised egg, called an embryo, is then returned to the woman's womb to grow and develop.

It can be carried out using your eggs and your partner'ssperm, or eggs and/or sperm from donors.

Who can have IVF?

The National Institute for Health and Care Excellence (NICE) has published fertility guidelines that make recommendations about who should have access to IVF treatment on the NHS in England and Wales.

These guidelines recommended that IVF should be offered to women under 43 years of age who have been trying to get pregnant through regular unprotected sex for two years, orwhohave had 12 cycles of Intrauterine insemination .

However, the final decision about who can have NHS-funded IVF in England is made bylocalClinical Commissioning Groups (CCGs), and their criteria may be stricter than those recommended by NICE.

If you're not eligible for NHS treatment, or you decide to pay for IVF, you can have treatment at a private clinic. Costs vary, but one cycle of treatment may cost up to 5,000 or more.

They can advise on how to improve your chances of having a baby.

If these measures don't work, your GP can refer youto a fertility specialist for a treatment such as IVF.

Readmore about getting started with IVF .

What happens during IVF

IVF involves six main stages:

Suppressing your natural cycle the menstrual cycle is suppressed with medication
Boosting your egg supply medication is used to encouragethe ovaries to produce more eggs than usual
Monitoring your progress and maturing your eggs an ultrasound scan is carried out to check the development of the eggs, and medication is used to help them mature
Collecting the eggs a needle is inserted into the ovaries, via the vagina, to remove the eggs
Fertilising the eggs the eggs are mixed with the sperm for a few days to allow them to be fertilised
Transferring the embryo(s) one or twofertilised eggs (embryos) are placed into the womb

Once the embryo(s) has been transferred into your womb, you'll need to wait two weeks before having a pregnancy test, to see if the treatment has worked.

Readmore about what happens duringIVF .

Chances of success

The success rate of IVF depends on the age of the woman undergoing treatment, as well as the cause of the infertility (if it's known).

Younger women are more likely to have a successful pregnancy. IVF isn't usually recommended for women above the age of 42, because the chances of a successful pregnancy are thought to be too low.

In 2010, the percentage of IVF treatments that resulted in alive birth was:

32.2% for women under 35
27.7% for women aged 35-37
20.8% for women aged 38-39
13.6% for women aged 40-42
5% for women aged 43-44
1.9% for women aged over 44

Maintaining a healthy weight and avoiding alcohol, smoking and caffeine during treatment may improve your chances of having a baby with IVF.

What are the risks?

IVF doesn't always result in pregnancy, and it can be both physically and emotionally demanding.You should be offered counselling to help you through the process.

There are also a number of health risks involved, including:

side effects from the medications used during treatment, such as hot flushes and headaches
multiple births (such as twins or triplets) this can be dangerous for both the mother and the children
an ectopic pregnancy where the embryo implants in the fallopian tubes, rather than in the womb
ovarian hyperstimulation syndrome (OHSS) where too many eggs develop in the ovaries

and the risks of IVF .