Oesophageal cancer
The exact cause ofoesophageal cancer is unknown,but certain things can increase the risk of it developing.
Gastro-oesophageal reflux disease (GORD) is a condition in which a weakness in the muscles above the stomach means stomach acid can travel up into the oesophagus.
In around 1 in 10 people with GORD,repeated damage from stomach acid over many years can eventually cause changes in the cells lining the oesophagus. This is called Barrett's oesophagus.
These abnormal cells are at an increased risk of becoming cancerous in the future, although the risk is still small.It's estimated thatone in every 10-20 people with Barrett's oesophagus will develop cancer within 10-20 years.
Drinking too much alcoholcauses irritation and inflammation in the lining of the oesophagus.
If the cells in the lining of your gullet become inflamed,they're more likely to become cancerous.
These substances irritate the cells that make up the lining of the oesophagus, which increases the likelihood that they will become cancerous.
The longer you smoke, the greater your risk of developing oesophageal cancer.
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Not eating enough fruit and vegetables may increase your risk of getting oesophageal cancer.
You should aim to eat at least five portions of fresh fruit and vegetables every day.
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Certain rare medical conditions can also increase your chances of developing cancer of the oesophagus, including:
Find out about oesophageal cancer, including what the symptoms are, why it occurs and what the main treatments are.
Find out about the main symptoms of oesophageal cancer and when to get medical advice.
Find out about the things that can increase your risk of oesophageal cancer, including GORD, alcohol, smoking, obesity and an unhealthy diet.
Find out how oesophageal is diagnosed, including which tests you may need to have.
Find out about the main treatments for oesophageal cancer, including surgery, chemotherapy and radiotherapy.
Find information and advice about living with oesophageal cancer, including how your diet may change and what financial support is available.
After discovering he had cancer of the oesophagus in 1998, keen marathon runner Clive Alexander had an oesophago-gastrectomy.