"Meningitis vaccine may also cut risk of 'untreatable' gonorrhoea, study says," is the headline in The Guardian. The news comes from the results of a study in New Zealand that found people…
"Meningitis vaccine may also cut risk of 'untreatable' gonorrhoea, study says," is the headline in The Guardian.
The publication of the study is timely – just last week the World Health Organization issued a warning about the rise in antibiotic-resistant strains of gonorrhoea.
The researchers claim this is the first vaccine to show any protective effect against gonorrhoea, but the vaccine in question is no longer in use.
A variant of the vaccine is currently given to babies in the UK as part of the routine NHS vaccination schedule. As the New Scientist magazine speculates, if the biological mechanism is discovered, we may see a sudden drop in gonorrhoea cases in 20 years' time.
But it's unlikely that a dedicated vaccine against gonorrhoea will be available for at least a few years. And that prospect is not a certainty by any means.
For now, the most effective way to prevent gonorrhoea is to always use a condom during sex, including oral and anal sex.
The study was carried out by researchers from Sexual Health Services, Waikato District Health Board, and the University of Auckland in New Zealand, and Cincinnati Children's Hospital in the US.
The research was funded by GSK Vaccines, a pharmaceutical company, and Auckland UniServices, a branch of the university that partners academics with industry. No conflicts of interest were declared.
The study was published in the peer-reviewed journal The Lancet.
The UK media's reporting was generally accurate – but the headlines weren't.
The Guardian's headline talks about "untreatable" gonorrhoea, but the study didn't look at whether any of the people had drug-resistant gonorrhoea or not. The research looked at data captured between 2004 and 2016, when drug-resistant gonorrhoea was less of a concern.
The Independent's headline – "World first as scientists develop vaccine that reduces chance of catching gonorrhoea" – is also inaccurate. The vaccine in question already existed, and it hasn't definitely been proven to reduce the chances of catching gonorrhoea.
Antimicrobial resistance has increased in recent years, and some strains of the infection are now resistant to drugs.
Researchers previously noted a decline in gonorrhoea diagnoses in New Zealand after a mass vaccination programme for meningococcal B, a serious cause of life-threatening infections such as meningitis and blood poisoning.
Meningitis B is caused by Neisseria meningitides, a bacteria similar to the one that causes gonorrhoea, so experts thought the MeNZB vaccine may be able to protect against both.
This type of research is useful for looking at a large population of people and examining trends and associations – but it can only show a link, not prove cause and effect.
A randomised controlled trial would be needed to do this, where the vaccine is offered to some people and not others, but this would be unethical.
They wanted to see if having the meningococcal B vaccine decreased the risk of getting gonorrhoea.
Of those involved, 1,241 people had a gonorrhoea-only diagnosis. Chlamydia-only diagnoses were used as the control group, which included 12,487 people.
Further analysis was done to include the 1,002 people who had both infections.
The researchers looked back over records from the New Zealand National Immunisation Register to identify which participants had received the MeNZB vaccine between 2004 and 2006.
They were able to link people diagnosed with gonorrhoea or chlamydia to their vaccine history through unique National Health Index numbers. They then adjusted the results for ethnicity, deprivation levels, geographical area and sex.
They also found:
"These results provide a proof of principle that can inform prospective vaccine development not only for gonorrhoea but also for meningococcal vaccines."
This large study found an association between having the MeNZB vaccine and a reduced likelihood of being diagnosed with gonorrhoea.
But it's difficult to form any firm conclusions because of the nature of the case and control groups.
It could just be down to pure chance and have nothing to do with the vaccine.
So before we celebrate the alleged "cure of gonorrhoea", there are many things to consider:
It's very much a case of "if" rather than "when" a gonorrhoea vaccine is developed. For now, the best way to protect yourself against gonorrhoea, chlamydia and other STIs is to always use a condom during vaginal, oral and anal sex.
Read more about how to have safe sex.