What is the cause?

Bullous pemphigoid is an autoimmune condition, which means the immune system attacks the body's own tissues and organs.

The person's immune system produces antibodies against the skin. These antibodies attack the basement membrane, which lies between the skin's top layer (epidermis) and the next layer (dermis), and holds the skin together. The skin layers start to separate and fluidbuilds up in between.

It'snot understood why autoimmune diseases like bullous pemphigoid happen, but it's thought something triggers the immune systemto attack the body's own tissues. Certain medicines and sunburn have been known toact as a trigger.

Symptoms usually come on unexpectedly.

Bullous pemphigoid isn't:

  • infectious
  • caused by an allergy
  • affected by diet or lifestyle
Content supplied by the NHS Website

Medically Reviewed by a doctor on 21 Dec 2018