What causes interstitial cystitis?

The exact cause of interstitial cystitis isn't clear. Unlike other types of cystitis , there's no obvious infection in the bladder and antibiotics don't help. In some people with the condition, the bladder is inflamed, ulcerated, scarred or stiff.

There are several theories about the possible cause of the condition, including:

  • damage to the bladder lining,which may mean urine canirritate the bladder and surrounding muscles and nerves
  • a problem with the pelvic floor muscles(used to control urination)
  • your immune system mistakenly attacking your bladder
  • an allergic reaction

It's also been suggested that interstitial cystitis may be a symptom of a more widespreadproblem, as it's been associated with conditions such as fibromyalgia , chronic fatigue syndrome (CFS) , irritable bowel syndrome (IBS) and lupus .

Content supplied by the NHS Website

Medically Reviewed by a doctor on 21 Dec 2018