Systemic lupus erythematosus
Lupus is a complex and poorly understood condition that affects many parts of the body.The symptomscan range from mild to life-threatening.
The term "lupus" is most often used to describe a more severe form of the condition called systemic lupus erythematosus (SLE).These pages focus on SLE.
However, there are several other types of lupus that just affect the skin, including:
Some medications can also cause lupus-like side effects, known as drug-induced lupus.
SLE can cause a wide range of symptoms, depending on the areas of the body affected. The most common symptoms are:
Many people have long periods with few or no symptoms before experiencing a sudden flare-up, where their symptoms are particularly severe.
Even mild cases can be distressing and have a considerable impact on a person's quality of life.
For reasons not yet understood, the immune system in people with SLE starts to attack and inflame healthy cells, tissue and organs.
As with other more common autoimmune conditions, such as rheumatoid arthritis , it's thought a combination of genetic and environmental factorsmay beresponsible for triggeringSLE in certain people.
Mostcases of SLE occur in women of childbearing age. The condition tends to be less common in white people of European origin and more common in those of African, Caribbean or Asian origin.
Readabout the causes of lupus .
There's currently no cure for SLE, but there are different medications that can help relieve many of the symptoms and reduce the chances of organ damage.
These medications include:
With good levels of support from friends, family and healthcare professionals, many people with SLE are able to manage their condition effectively.
Read about treating lupus .
If you have SLE, your clinical team will pass information about you on to the National Congenital Anomaly and Rare Diseases Registration Service (NCARDRS).
This helps scientists look for better ways to prevent and treat this condition. You can opt out of the register at any time.
The vast majority of people diagnosed with SLE will have a normal or near-normal life expectancy.
However, some people with SLE are at risk of life-threatening complications such as a heart attack or stroke as a result of damage to internal organs and tissues.
SLE, and some of the treatments for it, can also increase your risk of developing potentially serious infections.
Read about the complications of lupus .
Read about lupus, a complex and poorly understood condition that affects many parts of the body. It causes symptoms ranging from mild to life-threatening
Read about the symptoms of systemic lupus erythematosus (SLE), which can vary widely from person to person. Some people may only experience a few mild symptoms
Read about the causes of systemic lupus erythematosus (SLE). SLE is an autoimmune condition, which means it's caused by problems with the immune system
Read about diagnosing systemic lupus erythematosus (SLE), which can be difficult as it has similar symptoms to several other conditions
Read about treating systemic lupus erythematosus (SLE). There's currently no cure for SLE but treatments that can ease the symptoms and make it easier to live with are available
Read about complications of systemic lupus erythematosus (SLE). If SLE is mild or well-controlled, you may find it barely affects your day-to-day life