Symptoms of androgen insensitivity syndrome

Babies with androgen insensitivity syndrome (AIS) will be genetically male, but will either have female genitals or an appearance between male and female genitalia.

There are two main types of AIS, which affect people in different ways:

• complete androgen insensitivity (CAIS)
• partial androgen insensitivity (PAIS)

The main features of these two types are outlined below. For example, affected babies may have:

• a very small penis or an enlarged clitoris (the sexual organthat helps women reach sexual climax)
• partially undescended testicles
• hypospadias where thehole that carries urine out of the body is on the underside of the penis, rather than at the end

Children with PAIS are usually raised as boys, although they may experience poor penis development during puberty anddevelop small breasts. Mostchildrenwith PAIS raised as boys will be Infertility .

Some children with PAIS are raised as girls. Like thosewith CAIS, girls with PAIS will not have a womb or ovaries and will be unable to get pregnant.