What are the possible complications?

If typhus is not diagnosed and treated promptly, there is a risk of developing complications, including:

  • long-term hearing loss or tinnitus
  • low blood pressure
  • organ damage and kidney failure
  • secondary bacterial infection, such as pneumonia
  • seizures
  • confusion
  • drowsiness
  • gangrene

The patient may need to have hospital follow-up for some months after recovering from an attack of typhus to receive treatment for these long-term problems.

Brill-Zinsser disease

Some people who previously had epidemic typhus will develop a milder form of the disease years later called Brill-Zinsser disease.

This tends to happen when the bacteria were not properly killed off the first time and lie dormant (inactive) in the body. The bacteria then reactivate at a later date when the person's immune system is weak.

Brill-Zinsser disease will need treating again with antibiotics.

Content supplied by the NHS Website

Medically Reviewed by a doctor on 21 Dec 2018