Introduction

Bronchiectasis is a long-term condition where the airways of the lungs become abnormally widened, leading to a build-up of excess mucus that can make the lungs more vulnerable to infection.

The most common symptoms of bronchiectasis include:

• a persistent Cough that usually brings up phlegm (sputum)
• breathlessness

The severity of symptoms can vary widely. Some people have only a few symptoms that don't appear often, while others have wide-ranging dailysymptoms.

The symptoms tend to get worse if you develop an infection in your lungs.

When to see your GP

You should see your GP if you develop a persistent cough. While this may not becaused bybronchiectasis, it requires further investigation.

If your GP suspects you may have bronchiectasis, they'll refer you to a specialist in treating lung conditions (a respiratory consultant) for further tests.

Oxygen travels through these airways, ends up in tiny sacs called alveoli, and from there is absorbed into the bloodstream.

The inside walls of the bronchi are coated with sticky mucus, which protects against damage from particles moving down into the lungs.

In bronchiectasis, one or more of the bronchi are abnormally widened. This means more mucus than usual gathers there, which makes the bronchi more vulnerable to infection. If an infection does develop, the bronchi may be damaged again, so even more mucus gathers in them, and the risk of infection increases further.

Over time, this cycle can cause gradually worsening damage to the lungs.

Why it happens

Bronchiectasis can develop if the tissue and muscles that surround the bronchi are damaged or destroyed.

There are many reasons why this may happen. The three most common causes in the UKare:

• alung infection during childhood, such as pneumonia or whooping cough , that damages the bronchi
• underlying problems with the immune system (the bodys defence against infection) that make the bronchi more vulnerable to damage from an infection
• allergic bronchopulmonary aspergillosis (ABPA) an allergy to a certain type of fungi that can cause the bronchi to become inflamed if spores from the fungiare inhaled

However, in many cases of bronchiectasis, no obvious cause for the condition can be found (known as idiopathic bronchiectasis).

Who is affected

Bronchiectasis is thought to be uncommon. It's estimated that around 1 in every 1,000 adults in the UK have the condition.

It can affect anyone at any age, butsymptoms don't usually develop until middle age.

Over 12,000peoplewere admittedto hospital in England during 2013-14 with bronchiectasis. The majority of thesepeople were over 60 years old.

How bronchiectasis is treated

The damage caused to the lungs by bronchiectasis is permanent, but treatment can help relieve your symptoms and stop the damage getting worse.

The main treatments include:

• exercises and special devicesto help you clear mucus out of yourlungs
• medication to help improve airflow within the lungs
• antibiotics to treat any lung infections that develop

Surgeryis usually only considered for bronchiectasis in rare cases where other treatments haven't been effective, the damage to your bronchi is confined to a small area and you're in good general health.

One of the most serious complications is coughing up large amounts of blood, causedby one of the blood vessels in the lungs splitting. This problem can be life-threatening and may require emergency surgery to treat it.

Outlook

The outlook for people with bronchiectasis is highly variable and often depends on the underlying cause.

Living with bronchiectasis can be stressful and frustrating, but most people with the condition have a normal life expectancy. For people with very severe symptoms, however, bronchiectasis can be fatal if the lungs stop working properly.

Around 1,000 deaths reported in England and Wales each year are thought to becaused bybronchiectasis.

Information about you

If you havebronchiectasis, your clinical team may pass information about you on to the National Congenital Anomaly and Rare Diseases Registration Service (NCARDRS).

This helps scientists look for better ways to prevent and treat this condition. You can opt out of the register at any time.

Find out more about the register .

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