NMO is an autoimmune condition, which means a persons immune system (the bodys natural defence against illness and infection) reacts abnormally and attacks the body's tissues and organs.
An antibody against a protein called aquaporin-4 is present in the blood of up to 80% of people with NMO.
Antibodies are proteins produced by the body to destroy disease-carrying organisms and toxins.
In NMO, the immune system attacks aquaporin-4 which damages the myelin sheath(the protective layer that surrounds nerve cells in the brain and spinal cord and helps transmit nerve signals).
Neuromyelitis optica (NMO), also known as Devic's disease, is a rare neurological condition.
Optic neuritis is inflammation of the nerve that leads from the eye to the brain. It causes a reduction or Visual impairment , and can affect both eyes at the same time. Other symptoms of optic neuri
Transverse myelitis is inflammation of the spinal cord. It causes weakness in the arms and legs which can range from a mild 'heavy' feeling in one limb, to complete paralysis in all four limbs. It m
An attack orrelapse of NMO results in the nervous system becoming inflamed. The inflammation usually occurs in the optic nerve and spinal cord, and causes new symptoms or the recurrence of previous sy
NMO is an autoimmune condition, which means a persons immune system (the bodys natural defence against illness and infection) reacts abnormally and attacks the body's tissues and organs. An antibody
NMO is a rare condition. In Europe, it's estimated that there's one case of NMO for every 100,000 people. In the UK, it's thought that NMO affects less than 1,000 people. NMO can affect anyone but it
It's important that NMO is correctly diagnosed. It can sometimes be confused with multiple sclerosis , which also affects the brain and spinal cord and has similar symptoms. However, the treatment is
There's no cure for NMO, so treatment aims to manage attacks and symptoms, and prevent relapses. Every person with NMO is affected differently and some may have much milder symptoms than others. Howe
Optic neuritis (inflammation of the optic nerve) could affect your ability to drive. You have a legal obligation to tell the Driver and Vehicle Licensing Agency (DVLA) about any medical condition th
If you have NMO, your clinical team will pass information about you on to the National Congenital Anomaly and Rare Diseases Registration Service (NCARDRS). This helps scientists look for better ways