Pyoderma gangrenosum
What causes pyoderma gangrenosum?
The exact cause of pyoderma gangrenosum is not understood, but it's thought to be areaction to a disease or illness, such as the health conditions listed above.
However, about halfof all peoplewith pyoderma gangrenosum have none of these conditions, and thereis noobvious reason for it.
There is usually a high concentration of neutrophils(white blood cells involved in inflammation) in the affected tissue, which suggests it may be related to overactivity of the immune system.
The reaction may sometimes be triggered by minor skin damage or an injury for example, it may develop around the site of a stoma or surgical wound, a needle prick, a biopsy or an insect bite .
The skin reaction is not hereditary,so it's not passed from parents to their children.It's also not contagious,so can't be transferred from or to another person.
Medically Reviewed by a doctor on 21 Dec 2018
Introduction
Pyoderma gangrenosum is a rare skin condition that causes painful ulcers. It's usually treatable, but may take some time to heal and may leave some scarring.
When to seek medical advice
You should seek medical advice as soon as possible if you think you may have developed pyoderma gangrenosum. Either see your GP or contact your care team if you have one of the conditions mentioned be
Who is affected
Pyoderma gangrenosumis seen in men and women of any age, but usually affects young and middle-aged adults. People with the following health conditions are particularly susceptible: inflammatory b
What causes pyoderma gangrenosum?
The exact cause of pyoderma gangrenosum is not understood, but it's thought to be areaction to a disease or illness, such as the health conditions listed above. However, about halfof all peoplewith p
Diagnosing pyoderma gangrenosum
There is no specificblood test for pyoderma gangrenosum. If your doctor thinks you might have the condition, they may take a sample of your skin (a biopsy ) to examine under the microscope in a labor
How pyoderma gangrenosum is treated
Pyoderma gangrenosum is treatable, but may take some time to heal. Theres no clear evidence to suggest what the best treatment is, but the main treatments are outlined below. Care of the wound Dress
Outlook
In many people with pyoderma gangrenosum, the ulcers heal with relatively simple treatments. However, some scarring in the affected area is common. The progression of the condition varies from person
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